Research Paper Volume 13, Issue 8 pp 10955—10972

Hyperbaric oxygen therapy effectively alleviates D-galactose-induced-age-related cardiac dysfunction via attenuating mitochondrial dysfunction in pre-diabetic rats

Effect of HBOT on typical P-V loop tracings in pre-diabetic rats after induction of aging by D-gal. (A) A typical P-V loop tracing of sham-treated NDV rat. (B) A typical P-V loop tracing of sham-treated HFV rat. (C) A typical P-V loop tracing of sham-treated NDDg rat. (D) A typical P-V loop tracing of sham-treated HFDg rat. (E) A typical P-V loop tracing of HBOT-treated HFV rat. (F) A typical P-V loop tracing of HBOT-treated NDDg rat. (G) A typical P-V loop tracing of HBOT-treated HFDg rat. NDV, normal diet fed rats with vehicle; NDDg, normal diet fed rats with D-gal; HFV, high-fat diet fed rats with vehicle; HFDg, high-fat diet fed rats with D-gal.

Figure 3. Effect of HBOT on typical P-V loop tracings in pre-diabetic rats after induction of aging by D-gal. (A) A typical P-V loop tracing of sham-treated NDV rat. (B) A typical P-V loop tracing of sham-treated HFV rat. (C) A typical P-V loop tracing of sham-treated NDDg rat. (D) A typical P-V loop tracing of sham-treated HFDg rat. (E) A typical P-V loop tracing of HBOT-treated HFV rat. (F) A typical P-V loop tracing of HBOT-treated NDDg rat. (G) A typical P-V loop tracing of HBOT-treated HFDg rat. NDV, normal diet fed rats with vehicle; NDDg, normal diet fed rats with D-gal; HFV, high-fat diet fed rats with vehicle; HFDg, high-fat diet fed rats with D-gal.