Research Paper Volume 13, Issue 8 pp 10955—10972

Hyperbaric oxygen therapy effectively alleviates D-galactose-induced-age-related cardiac dysfunction via attenuating mitochondrial dysfunction in pre-diabetic rats

Effect of HBOT on heart rate variability and blood pressure in pre-diabetic rats after induction of aging by D-gal. (A) Heart rate variability. (B) Systolic blood pressure. (C) Diastolic blood pressure. (D) Mean arterial blood pressure. NDV, normal diet fed rats with vehicle; NDDg, normal diet fed rats with D-gal; HFV, high-fat diet fed rats with vehicle; HFDg, high-fat diet fed rats with D-gal; LF/HF, low frequency/high frequency ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; HBOT, hyperbaric oxygen therapy. (n = 8/group). *P

Figure 4. Effect of HBOT on heart rate variability and blood pressure in pre-diabetic rats after induction of aging by D-gal. (A) Heart rate variability. (B) Systolic blood pressure. (C) Diastolic blood pressure. (D) Mean arterial blood pressure. NDV, normal diet fed rats with vehicle; NDDg, normal diet fed rats with D-gal; HFV, high-fat diet fed rats with vehicle; HFDg, high-fat diet fed rats with D-gal; LF/HF, low frequency/high frequency ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; HBOT, hyperbaric oxygen therapy. (n = 8/group). *P < 0.05.