Research Paper Volume 13, Issue 9 pp 12996—13005

Azilsartan ameliorates ox-LDL-induced endothelial dysfunction via promoting the expression of KLF2

Azilsartan mitigated ox-LDL-induced expression of occludin. Cells were stimulated with ox-LDL (100 μg/mL) in the presence or absence of Azilsartan (6 μM) for 24 hours. (A) Gene expression of Occludin; (B) Protein of Occludin (****, P

Figure 6. Azilsartan mitigated ox-LDL-induced expression of occludin. Cells were stimulated with ox-LDL (100 μg/mL) in the presence or absence of Azilsartan (6 μM) for 24 hours. (A) Gene expression of Occludin; (B) Protein of Occludin (****, P<0.0001 vs. vehicle group; ###, P<0.001 vs. ox-LDL group, N=6 for each group).