Research Paper Volume 13, Issue 10 pp 13822—13845

Development and validation of epithelial mesenchymal transition-related prognostic model for hepatocellular carcinoma

Construction of a 10 gene based EMT-related prognostic signature for HCC in TCGA-LIHC cohort. (A) The risk score distribution of HCC patients in TCGA-LIHC cohorts. (B) Duration and survival status of HCC patients. (C) Kaplan-Meier analysis of ten-gene signature in TCGA-LIHC cohort. (D) Heatmaps of the ten gene signature relative expression. (E) Time-dependent ROC analysis of ten-gene signature in training set. (F) Time-dependent ROC analysis of ten-gene signature in testing set. (G) Time-dependent ROC analysis of ten-gene signature in total cohort. HCC, hepatocellular carcinoma; TCGA, The Cancer Genome Atlas; ROC, receiver operating characteristic curve.

Figure 2. Construction of a 10 gene based EMT-related prognostic signature for HCC in TCGA-LIHC cohort. (A) The risk score distribution of HCC patients in TCGA-LIHC cohorts. (B) Duration and survival status of HCC patients. (C) Kaplan-Meier analysis of ten-gene signature in TCGA-LIHC cohort. (D) Heatmaps of the ten gene signature relative expression. (E) Time-dependent ROC analysis of ten-gene signature in training set. (F) Time-dependent ROC analysis of ten-gene signature in testing set. (G) Time-dependent ROC analysis of ten-gene signature in total cohort. HCC, hepatocellular carcinoma; TCGA, The Cancer Genome Atlas; ROC, receiver operating characteristic curve.