Figure 5. Validation of the 7-ZNF-gene prognostic signature in a GEO dataset. (A) Distribution and median value of the risk scores in the GSE48276 cohort. (B) Survival status of low-risk and high-risk patients. (C) Heatmap of the expression profiles of the 7-ZNF-gene signature. (D) Time-dependent ROC curve of the prognostic signature. (E) Survival analysis of signature-defined risk groups.