Research Paper Volume 13, Issue 9 pp 13225—13238

TRIM14 regulates melanoma malignancy via PTEN/PI3K/AKT and STAT3 pathways

TRIM14 was upregulated in melanoma cell lines. The human epidermal melanocytes (HEMa-LP) and melanoma cell lines (A375, SK-MEL-24, WM451, WM35) were used to detect the mRNA level of TRIM14 using RT-qPCR (A) and the protein expression of TRIM14 using western blot (B). *, **, ***p

Figure 1. TRIM14 was upregulated in melanoma cell lines. The human epidermal melanocytes (HEMa-LP) and melanoma cell lines (A375, SK-MEL-24, WM451, WM35) were used to detect the mRNA level of TRIM14 using RT-qPCR (A) and the protein expression of TRIM14 using western blot (B). *, **, ***p < 0.05, 0.01, 0.001 vs HEMa-LP.