Research Paper Volume 13, Issue 10 pp 13941—13953

NEAT 1 knockdown enhances the sensitivity of human non-small-cell lung cancer cells to anlotinib

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Figure 5. NEAT1 siRNA3 facilitated the cytotoxic effect of anlotinib through downregulation of Wnt/β-catenin signaling pathway. The expression of p-VEGFR2, VEGFR2, β-catenin, and c-Myc were evaluated by western blot. β-actin was used as an inner control. (A) The expression of p-VEGFR2, VEGFR2, β-catenin, and c-Myc in A549 cells and (B) NCI-H1975 cells. **P < 0.01 compared with the control group.