Research Paper Volume 13, Issue 11 pp 14924—14939

Nucleolar small molecule RNA SNORA75 promotes endometrial receptivity by regulating the function of miR-146a-3p and ZNF23

class="figure-viewer-img"

Figure 2.

SNORA75 promotes the proliferation, migration and invasion of endometrial epithelial cells. (A) The expression of SNORA75 in EEC cells was detected by in situ hybridization. (B) CCK-8 was used to detect the effect of SNORA75 on the proliferation of EEC, Ishikawa and RL952 cells. (C) The colony formation assay was used to detect the effect of SNORA75 on the proliferation of EEC, Ishikawa and RL952 cells. (D) The apoptosis of EEC, Ishikawa and RL952 cells was detected by flow cytometry. (E) The effect of SNORA75 on the migration of EEC, Ishikawa and RL952 cells was detected by the cell scratch assay. (F) Transwell assays were used to detect the invasion of EEC, Ishikawa and rl952 cells. "##" indicates that, compared with the pLKO.1-vector group, P < 0.01. "**" indicates that, compared with the pLVX-vector group, P < 0.01.