Research Paper Volume 13, Issue 10 pp 14001—14014

Adalimumab ameliorates memory impairments and neuroinflammation in chronic cerebral hypoperfusion rats

ADA inhibited NF-κB signaling in CCH rats. (A) Representative blots for p-p65, p65 and STAT3 in the different groups are shown. β-Actin was used as loading control. (B–D) Quantification of the optical intensity of p-p65 (B), p65 (C) and STAT3 (D). (E) NF-κB activity was evaluated by ELISA kits. All values are expressed as the mean ± SEM (n = 6). **p ##p

Figure 7. ADA inhibited NF-κB signaling in CCH rats. (A) Representative blots for p-p65, p65 and STAT3 in the different groups are shown. β-Actin was used as loading control. (BD) Quantification of the optical intensity of p-p65 (B), p65 (C) and STAT3 (D). (E) NF-κB activity was evaluated by ELISA kits. All values are expressed as the mean ± SEM (n = 6). **p < 0.01 vs. the sham group; ##p < 0.01 vs. the CCH group.