Research Paper Volume 13, Issue 9 pp 13287—13299

Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway

Glioma-derived exosomes inhibit glioma cell apoptosis. (A) Apoptosis of glioma cells treated with exosomes isolated from A172 or U373 cells, as detected by flow cytometry analysis. (B) Protein expression of apoptosis-related proteins Bcl-2, cleaved-caspase3, and cleaved-caspase9. (C) Protein expression of invasion-related proteins E-cadherin, N-cadherin, Vimentin, and MMP9. Data were represented as mean ± SD. ** p

Figure 2. Glioma-derived exosomes inhibit glioma cell apoptosis. (A) Apoptosis of glioma cells treated with exosomes isolated from A172 or U373 cells, as detected by flow cytometry analysis. (B) Protein expression of apoptosis-related proteins Bcl-2, cleaved-caspase3, and cleaved-caspase9. (C) Protein expression of invasion-related proteins E-cadherin, N-cadherin, Vimentin, and MMP9. Data were represented as mean ± SD. ** p < 0.01.