Research Paper Volume 13, Issue 10 pp 14053—14064

Role of LINC01592 in TGF-β1-induced epithelial-mesenchymal transition of retinal pigment epithelial cells

Expression of EMT marker proteins following induction of RPE cells with TGF-β1, as detected by western blot. E-cadherin expression was downregulated, whereas expression of α-SMA and Snail were upregulated in the group induced by TGF-β1 (A, B). The difference of expression levels between the two groups was statistically significant (P  0.05).

Figure 2. Expression of EMT marker proteins following induction of RPE cells with TGF-β1, as detected by western blot. E-cadherin expression was downregulated, whereas expression of α-SMA and Snail were upregulated in the group induced by TGF-β1 (A, B). The difference of expression levels between the two groups was statistically significant (P < 0.05).