Research Paper Volume 13, Issue 10 pp 14053—14064

Role of LINC01592 in TGF-β1-induced epithelial-mesenchymal transition of retinal pigment epithelial cells

Knockdown of LINC01592 decreased the proliferation and migration of RPE cells. Migration of RPE cells in each group was observed under a microscope at 0, 24, and 48 h (A). The residual scratch area of RPE cells in each group after transfection and induction by TGF-β1 for 48 h (B). Viability of RPE cells was detected by CCK-8 after transfection and induction by TGF-β1 for 48 h (C). The difference of expression levels between groups was statistically significant (P  0.05).

Figure 6. Knockdown of LINC01592 decreased the proliferation and migration of RPE cells. Migration of RPE cells in each group was observed under a microscope at 0, 24, and 48 h (A). The residual scratch area of RPE cells in each group after transfection and induction by TGF-β1 for 48 h (B). Viability of RPE cells was detected by CCK-8 after transfection and induction by TGF-β1 for 48 h (C). The difference of expression levels between groups was statistically significant (P < 0.05).