Research Paper Volume 13, Issue 10 pp 14131—14158

Downregulation of USP18 reduces tumor-infiltrating activated dendritic cells in extranodal diffuse large B cell lymphoma patients

The KEGG pathways downstream of USP18 in EN DLBCL. (A) The coexpression heatmap of USP18 and KEGG pathways selected by GSVA. (B) The Venn plot to show overlapped KEGG pathways in both GSVA and GSEA; (C) The GSEA of overlapped KEGG pathways; (D) The GSEA of MAPK pathway; (E) The correlation between USP18 and MAPK signaling pathway. Abbreviations: GSVA, Gene set variation analysis; GSEA, Gene set enrichment analysis; MAPK, Mitogen-activated protein kinase.

Figure 5. The KEGG pathways downstream of USP18 in EN DLBCL. (A) The coexpression heatmap of USP18 and KEGG pathways selected by GSVA. (B) The Venn plot to show overlapped KEGG pathways in both GSVA and GSEA; (C) The GSEA of overlapped KEGG pathways; (D) The GSEA of MAPK pathway; (E) The correlation between USP18 and MAPK signaling pathway. Abbreviations: GSVA, Gene set variation analysis; GSEA, Gene set enrichment analysis; MAPK, Mitogen-activated protein kinase.