Research Paper Volume 13, Issue 10 pp 14304—14321

Accumulation of CD45RO+CD8+ T cells is a diagnostic and prognostic biomarker for clear cell renal cell carcinoma

CD45RO combined with related proteins is an effectively diagnostic marker for ccRCC. (A) The relations between UCHL1 and related genes. Color and line weight represent correlation coefficients. Red: positively related Green: negatively related. (B) The correlation and distribution of 2 groups among clinical characteristics in ccRCC patients. Expression level: log2(FPKM+0.01). (C) Preventive images of ccRCC tissues and normal renal tissues incubated with UCHL1, CD36, HMGB3, IKBKE, PTLP and PTGES anti-body. (D) ROC curve analyses for evaluating the diagnostic potential of UCHL1, CD36 and HMGB3 for ccRCC. (E) ROC curve analyses for evaluating the diagnostic potential of UCHL1- CD36, UCHL1 - HMGB3, and HMGB3- CD36 for ccRCC. (F) ROC curve analyses for evaluating the diagnostic potential of UCHL1- CD36- HMGB3 for ccRCC.

Figure 7. CD45RO combined with related proteins is an effectively diagnostic marker for ccRCC. (A) The relations between UCHL1 and related genes. Color and line weight represent correlation coefficients. Red: positively related Green: negatively related. (B) The correlation and distribution of 2 groups among clinical characteristics in ccRCC patients. Expression level: log2(FPKM+0.01). (C) Preventive images of ccRCC tissues and normal renal tissues incubated with UCHL1, CD36, HMGB3, IKBKE, PTLP and PTGES anti-body. (D) ROC curve analyses for evaluating the diagnostic potential of UCHL1, CD36 and HMGB3 for ccRCC. (E) ROC curve analyses for evaluating the diagnostic potential of UCHL1- CD36, UCHL1 - HMGB3, and HMGB3- CD36 for ccRCC. (F) ROC curve analyses for evaluating the diagnostic potential of UCHL1- CD36- HMGB3 for ccRCC.