Figure 5. IRS1 and KLF10 are targets of miRNA-126. (A) The predicted binding sites between miRNA-126 and IRS1, and KLF10, and relative luciferase activity in IRS1 and KLF10 3′UTR (wild-type/mutant) and miRNA-126. (B) mRNA levels of IRS1 and KLF10 in MDSCs. (C) Protein expressions of IRS1 and KLF10 in MDSCs. Data are shown as the means ± SD. *P < 0.05, **P < 0.01.