Research Paper Volume 13, Issue 11 pp 15100—15113

Hsa_circ_0032131 knockdown inhibits osteoarthritis progression via the miR-502-5p/PRDX3 axis

Silencing of hsa

Figure 8. Silencing of hsa_circ_0032131 alleviated OA progression in vivo by inhibiting Trx1/STAT3 signaling. (A) The expression of PRDX3, STAT3, p-STAT3, and Trx1 in rat tissues was detected by western blotting. (B) The relative expression of PRDX3 was quantified by normalizing it to that of β-actin. (C) The relative expression of p-STAT3 was quantified by normalizing it to that of β-actin. (D) The relative expression of Trx1 was quantified by normalizing it to that of β-actin. **p < 0.01 compared with the control. ##p < 0.01 compared with OA.