Research Paper Volume 13, Issue 11 pp 15164—15192

Identification and validation of a novel eight mutant-derived long non-coding RNAs signature as a prognostic biomarker for genome instability in low-grade glioma

Correlation analysis of the 8 genomic instability-associated lncRNAs with infiltration of each subtype of immune cells. (A) Correlation coefficients for M0 macrophages, M1 macrophages, memory resting CD4 T cells, and CD8 T cells for the training set were 0.23, 0.26 0.27, 0.22 (p p p B) The correlation coefficients among the risk scores for M1 macrophages, memory resting CD4 T cells, activated mast cells and monocytes for the validation set were 0.31, 0.29, –0.27 and –0.2, respectively (p

Figure 6. Correlation analysis of the 8 genomic instability-associated lncRNAs with infiltration of each subtype of immune cells. (A) Correlation coefficients for M0 macrophages, M1 macrophages, memory resting CD4 T cells, and CD8 T cells for the training set were 0.23, 0.26 0.27, 0.22 (p < 0.001), whereas the correlation coefficient for activated mast cells was R = –0.21 (p < 0.05) and the correlation coefficient for monocytes was R = –0.29 (p < 0.001). (B) The correlation coefficients among the risk scores for M1 macrophages, memory resting CD4 T cells, activated mast cells and monocytes for the validation set were 0.31, 0.29, –0.27 and –0.2, respectively (p < 0.05).