Research Paper Volume 13, Issue 11 pp 15320—15335

Cistanche deserticola polysaccharides alleviate cognitive decline in aging model mice by restoring the gut microbiota-brain axis

CDPS inhibits peripheral inflammation and improves immune function by regulating amino acid and purine metabolism. (A) Pathway enrichment analyses list of serum metabolites in the WT, Mod and CDPS group of mice. (B) Bubble chart of pathway enrichment analyses of serum metabolites in the WT, Mod and CDPS group of mice. (C) The serum concentration of various amino acids (creatinine, valine, L-(-)-Methionine, o-Toluidine, N-Ethylaniline, uric acid, and proline) in the ABX and Cy versus WT group of mice. (D, E) MetaboAnalyst results show the correlation between the differentially expressed metabolites and human diseases.

Figure 8. CDPS inhibits peripheral inflammation and improves immune function by regulating amino acid and purine metabolism. (A) Pathway enrichment analyses list of serum metabolites in the WT, Mod and CDPS group of mice. (B) Bubble chart of pathway enrichment analyses of serum metabolites in the WT, Mod and CDPS group of mice. (C) The serum concentration of various amino acids (creatinine, valine, L-(-)-Methionine, o-Toluidine, N-Ethylaniline, uric acid, and proline) in the ABX and Cy versus WT group of mice. (D, E) MetaboAnalyst results show the correlation between the differentially expressed metabolites and human diseases.