Research Paper Volume 13, Issue 11 pp 15501—15510

LncRNA BCRT1 facilitates osteosarcoma progression via regulating miR-1303/FGF7 axis

BCRT1 induced osteosarcoma cell cycle and proliferation via modulating FGF7 expression. (A) The level of FGF7 in four osteosarcoma cell lines (MG-63, HOS, SAOS-2 and U2OS) and hFOB was detected using qRT-PCR assay. (B) The expression of FGF7 was determined by qRT-PCR assay. (C) The expression of cyclin D1 was measured using qRT-PCR assay. (D) The expression of CKD2 was measured using qRT-PCR assay. (E) The level of ki-67 was detected using qRT-PCR assay. (F) Cell proliferation was measured by CCK-8 assay. (G) Inhibition expression of FGF7 suppressed cell cycle in BCRT1-overexpressing MG-63 cell. *p

Figure 6. BCRT1 induced osteosarcoma cell cycle and proliferation via modulating FGF7 expression. (A) The level of FGF7 in four osteosarcoma cell lines (MG-63, HOS, SAOS-2 and U2OS) and hFOB was detected using qRT-PCR assay. (B) The expression of FGF7 was determined by qRT-PCR assay. (C) The expression of cyclin D1 was measured using qRT-PCR assay. (D) The expression of CKD2 was measured using qRT-PCR assay. (E) The level of ki-67 was detected using qRT-PCR assay. (F) Cell proliferation was measured by CCK-8 assay. (G) Inhibition expression of FGF7 suppressed cell cycle in BCRT1-overexpressing MG-63 cell. *p<0.05, **p<0.01 and ***p<0.001.