Research Paper Volume 13, Issue 11 pp 15548—15568

Identification of a nomogram based on an 8-lncRNA signature as a novel diagnostic biomarker for childhood acute lymphoblastic leukemia

LINC01278 affects apoptosis in CCRF-CEM cells. (A) The BAX, Caspase1, Cytc and Bcl-2 mRNA expression of the CCRF-CEM cell model with LINC01278 knock down. (B) The miR-500b-3p expression of the CCRF-CEM cell model with LINC01278 knock down. (C) The proliferation of the CCRF-CEM cell model with LINC01278 knock down. (D, E) The protein expression of BAX, Caspase1, Cytc and Bcl-2 in the CCRF-CEM cell model with LINC01278 knock down. NC indicates normal control; drug indicates a control group that was exposed to a drug. (F, G) The apoptosis of the CCRF-CEM cell model with LINC01278 control group with positive drugs down; *P

Figure 7. LINC01278 affects apoptosis in CCRF-CEM cells. (A) The BAX, Caspase1, Cytc and Bcl-2 mRNA expression of the CCRF-CEM cell model with LINC01278 knock down. (B) The miR-500b-3p expression of the CCRF-CEM cell model with LINC01278 knock down. (C) The proliferation of the CCRF-CEM cell model with LINC01278 knock down. (D, E) The protein expression of BAX, Caspase1, Cytc and Bcl-2 in the CCRF-CEM cell model with LINC01278 knock down. NC indicates normal control; drug indicates a control group that was exposed to a drug. (F, G) The apoptosis of the CCRF-CEM cell model with LINC01278 control group with positive drugs down; *P<0.05.