Research Paper Volume 13, Issue 11 pp 15569—15579

Repressor element-1 silencing transcription factor regulates glutamate receptors and immediate early genes to affect synaptic plasticity

REST knockdown reduced the synaptophysin (SYN) and PSD-95 expression in the primary mouse hippocampal neurons. (A) REST was successfully knocked down in the primary mouse hippocampal neurons. n = 3. (B) SYN and PSD-95 was deregulated after knockdown of REST. n = 3. Independent experiments were performed three times. Data are expressed as mean ± SEM. *p

Figure 2. REST knockdown reduced the synaptophysin (SYN) and PSD-95 expression in the primary mouse hippocampal neurons. (A) REST was successfully knocked down in the primary mouse hippocampal neurons. n = 3. (B) SYN and PSD-95 was deregulated after knockdown of REST. n = 3. Independent experiments were performed three times. Data are expressed as mean ± SEM. *p < 0.05.