Research Paper Volume 13, Issue 11 pp 15569—15579

Repressor element-1 silencing transcription factor regulates glutamate receptors and immediate early genes to affect synaptic plasticity

Inhibition of combination between REST and ARC by Aβ. (A) The REST-binding site at -75 to -19 bp of ARC gene. (B) Aβ reduced the interaction between REST and ARC. n = 3. (C) The TATA-box of ARC at -28 bp as shown by the prediction of EPD. Independent experiments were performed three times. Data are expressed as mean ± SEM. *p

Figure 5. Inhibition of combination between REST and ARC by Aβ. (A) The REST-binding site at -75 to -19 bp of ARC gene. (B) Aβ reduced the interaction between REST and ARC. n = 3. (C) The TATA-box of ARC at -28 bp as shown by the prediction of EPD. Independent experiments were performed three times. Data are expressed as mean ± SEM. *p < 0.05 vs the corresponding control group.