Research Paper Volume 13, Issue 12 pp 16485—16499

Cell landscape atlas for patients with chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy constructed using single-cell RNA sequencing

Characterization of macrophages and mast cells in pulmonary endarterectomized tissues of CTEPH patients. (A) Violin plot showing the marker genes of macrophages, including CD68 and CD163. (B) GO enrichment analysis of marker genes of macrophages. (C) Violin plot showing mast cell marker genes, including TPSB2, SLC18A2, and TPSAB1. (D) GO enrichment analysis of mast cell marker genes. Abbreviations: CTEPH: chronic thromboembolic pulmonary hypertension; GO: Gene ontology.

Figure 5. Characterization of macrophages and mast cells in pulmonary endarterectomized tissues of CTEPH patients. (A) Violin plot showing the marker genes of macrophages, including CD68 and CD163. (B) GO enrichment analysis of marker genes of macrophages. (C) Violin plot showing mast cell marker genes, including TPSB2, SLC18A2, and TPSAB1. (D) GO enrichment analysis of mast cell marker genes. Abbreviations: CTEPH: chronic thromboembolic pulmonary hypertension; GO: Gene ontology.