Research Paper Volume 13, Issue 13 pp 17237—17252

Association between Alzheimer’s disease genes and trajectories of cognitive function decline in Han Chinese in Taiwan

Mean trajectories of cognitive function for individuals carrying specific genotypes in the APOE gene and SORL1 rs3737529 SNPa. AIn the figure legend, ApoE4 (0/1/2) means that individuals are carrying zero, one, or two copies of the ε4 allele in the APOE gene; rs3737529 (CC/CT/TT) means that individuals are carrying the CC, CT, or TT genotypes in SORL1 rs3737529. Note: The full sample of 255 AD and 44 MCI patients at baseline were analyzed.

Figure 1. Mean trajectories of cognitive function for individuals carrying specific genotypes in the APOE gene and SORL1 rs3737529 SNPa. AIn the figure legend, ApoE4 (0/1/2) means that individuals are carrying zero, one, or two copies of the ε4 allele in the APOE gene; rs3737529 (CC/CT/TT) means that individuals are carrying the CC, CT, or TT genotypes in SORL1 rs3737529. Note: The full sample of 255 AD and 44 MCI patients at baseline were analyzed.