Research Paper Volume 13, Issue 13 pp 17442—17461

Prognostic signatures associated with high infiltration of Tregs in bone metastatic prostate cancer

Immune infiltration and immunofluorescence identification. (A) Correlation of gene expression levels of COL3A1, EEF2, FN1, RAC1, and SDC2 with tumor purity and CD4+ T cells. (B) Tumor infiltrating lymphocytes profiles in the BM PCa (1. BM tumor, 2 normal tissues). Normal tissue (C) and BM tumor (D) immunofluorescence labeling for CD4 (red) and FOXP3 (green), as well as merged images. (n =6, P

Figure 6. Immune infiltration and immunofluorescence identification. (A) Correlation of gene expression levels of COL3A1, EEF2, FN1, RAC1, and SDC2 with tumor purity and CD4+ T cells. (B) Tumor infiltrating lymphocytes profiles in the BM PCa (1. BM tumor, 2 normal tissues). Normal tissue (C) and BM tumor (D) immunofluorescence labeling for CD4 (red) and FOXP3 (green), as well as merged images. (n =6, P < 0.05, 200X).