Research Paper Advance Articles

An association study in the Taiwan Biobank elicits three novel candidates for cognitive aging in old adults: NCAM1, TTC12 and ZBTB20

Locus zoom plot for the NCAM1-TTC12-ANKK1-DRD2 locus for cognitive aging in the Taiwan Biobank. SNPs are shown by their position on the chromosome against their association (−log10 P) with cognitive aging. SNPs are colored to reflect their linkage disequilibrium with the top SNP (rs138333675) in TTC12. Estimated recombination rates are plotted in cyan using Asian subjects from the 1000 Genomes Project. This plot was generated using LocusZoom.

Figure 1. Locus zoom plot for the NCAM1-TTC12-ANKK1-DRD2 locus for cognitive aging in the Taiwan Biobank. SNPs are shown by their position on the chromosome against their association (−log10 P) with cognitive aging. SNPs are colored to reflect their linkage disequilibrium with the top SNP (rs138333675) in TTC12. Estimated recombination rates are plotted in cyan using Asian subjects from the 1000 Genomes Project. This plot was generated using LocusZoom.