Research Paper Volume 13, Issue 15 pp 19908—19919

A circular RNA, circSMARCA5, inhibits prostate cancer proliferative, migrative, and invasive capabilities via the miR-181b-5p/miR-17-3p-TIMP3 axis

circSMARCA5 expression in prostate tumors. (A) The circSMARCA5 expression pattern in prostate cancer samples and benign controls was determined by qRT-PCR. (B) circSMARCA5 levels were measured in RWPE-1, DU145, LNCaP, and PC3 cells. *, **, *** represent p ≤ 0.05, p ≤ 0.01, p ≤ 0.001, respectively. Assays were performed at least three times.

Figure 1. circSMARCA5 expression in prostate tumors. (A) The circSMARCA5 expression pattern in prostate cancer samples and benign controls was determined by qRT-PCR. (B) circSMARCA5 levels were measured in RWPE-1, DU145, LNCaP, and PC3 cells. *, **, *** represent p ≤ 0.05, p ≤ 0.01, p ≤ 0.001, respectively. Assays were performed at least three times.