Research Paper Volume 13, Issue 16 pp 20598—20608

Knockdown of hsa_circ_0091994 constrains gastric cancer progression by suppressing the miR-324-5p/HMGA1 axis

Bioinformatics analysis to identify DEcircRNAs in GC. (A) Heat map indicating DEcircRNAs in GC tissue. (B) Volcano plot of DEcircRNAs. Highly downregulated and upregulated genes indicated in green and red, respectively. P-value 10 p-value > 1.3) and |log2(fold change)| > 1.5 were thresholds. (C) Survival analysis demonstrating the relationship between the level of FLNA (the host gene of hsa

Figure 1. Bioinformatics analysis to identify DEcircRNAs in GC. (A) Heat map indicating DEcircRNAs in GC tissue. (B) Volcano plot of DEcircRNAs. Highly downregulated and upregulated genes indicated in green and red, respectively. P-value < 0.05 (-log10 p-value > 1.3) and |log2(fold change)| > 1.5 were thresholds. (C) Survival analysis demonstrating the relationship between the level of FLNA (the host gene of hsa_circ_0091994) and survival rate of GC patients.