Research Paper
Regulation of bone and fat balance by fructus ligustri lucidi in ovariectomized mice
Figure 2. FLL suppresses bone loss and reduces fat weight in OVX mice. (A) Body weights of OVX mice 8 weeks post-operatively. Treatment with FLL decreased body weight significantly. (B) Bone mineral density (BMD) in the femurs of OVX mice decreased significantly compared to the sham group, and estrogen and FLL significantly augmented BMD in OVX mice. The body fat and (C) lean content (D) of each group were evaluated by NMR body composition analyzer after 8 weeks. (E–G) The indices for liver, kidney and spleen among groups. #P < 0.05 compared with sham; ##P < 0.01 compared with sham; *P < 0.05 compared OVX; **P < 0.01 compared OVX (n = 10).