COVID-19 Research Paper Volume 13, Issue 17 pp 20860—20885

Circulating acetylated polyamines correlate with Covid-19 severity in cancer patients

Identification of metabolites discriminating cancer patients according to the duration of SARS-CoV-2 shedding. Volcano plot comparing Covid-19 patients with short versus long viral shedding (determined by RT-PCT of nasopharyngeal PCRs, the threshold between short and long shedding being 40 days), classified by chemical classes. X-axis: log2 fold change of metabolites; Y-axis: fold change of –log10 P value determined by the Mann–Whitney test.

Figure 5. Identification of metabolites discriminating cancer patients according to the duration of SARS-CoV-2 shedding. Volcano plot comparing Covid-19 patients with short versus long viral shedding (determined by RT-PCT of nasopharyngeal PCRs, the threshold between short and long shedding being 40 days), classified by chemical classes. X-axis: log2 fold change of metabolites; Y-axis: fold change of –log10 P value determined by the Mann–Whitney test.