Research Paper Volume 13, Issue 19 pp 22792—22801

Identification of hub genes and key pathways of paraquat-induced human embryonic pulmonary fibrosis by bioinformatics analysis and in vitro studies

Module analysis of the PPI network. Up-regulated genes are marked in light red, down-regulated genes are marked in light blue (A). The most significant module generated from the PPI network. JUNB, FOSL2, SOCS3, DUSP1, CCL2, CEBPD, CXCL2, ATF3 protein–protein interaction (B). Up-regulated genes are marked in light red, down-regulated genes are marked in light blue.

Figure 5. Module analysis of the PPI network. Up-regulated genes are marked in light red, down-regulated genes are marked in light blue (A). The most significant module generated from the PPI network. JUNB, FOSL2, SOCS3, DUSP1, CCL2, CEBPD, CXCL2, ATF3 protein–protein interaction (B). Up-regulated genes are marked in light red, down-regulated genes are marked in light blue.