Research Paper Volume 13, Issue 19 pp 23245—23261

Identification of potential target genes of non-small cell lung cancer in response to resveratrol treatment by bioinformatics analysis

The process of screening candidate genes. (A) The DEGs in A549 cells treated with or without 25 microM resveratrol for 48 hours. Fold change >1 and p-value B) The DEGs in NSCLC tissue and adjacent normal tissue. Fold change >1 and p-value C) Genes down-regulated in NSCLC and unregulated by resveratrol in A549 (n = 135). (D) Genes unregulated in NSCLC and down-regulated by resveratrol in A549 (n = 33). (E) Genes down-regulated in both NSCLC and resveratrol treated A549 (n = 47). (F) Genes upregulated in both NSCLC and resveratrol treated A549 (n = 56).

Figure 1. The process of screening candidate genes. (A) The DEGs in A549 cells treated with or without 25 microM resveratrol for 48 hours. Fold change >1 and p-value <0.05 was considered to be significant. (B) The DEGs in NSCLC tissue and adjacent normal tissue. Fold change >1 and p-value <0.05 was considered to be significant (C) Genes down-regulated in NSCLC and unregulated by resveratrol in A549 (n = 135). (D) Genes unregulated in NSCLC and down-regulated by resveratrol in A549 (n = 33). (E) Genes down-regulated in both NSCLC and resveratrol treated A549 (n = 47). (F) Genes upregulated in both NSCLC and resveratrol treated A549 (n = 56).