Research Paper Advance Articles

Resveratrol promotes axonal regeneration after spinal cord injury through activating Wnt/β-catenin signaling pathway

iCRT3 significantly reversed the influence of resveratrol on apoptosis in vitro. (A) Influence of iCRT3 on the Wnt signaling related proteins expression through western blotting; (B) CRT3 significantly inhibited the protein expression of Wnt signaling related proteins; (C) iCRT3 significantly inhibited the mRNA expression of Wnt signaling related proteins; (D) The influence of iCRT3 on the apoptosis was investigated; (E) iCRT3 significantly reversed the influence of resveratrol on apoptosis in vitro; (F) iCRT3 significantly reversed the influence of resveratrol on cell proliferation in vitro; (G) Influence of iCRT3 on the protein expression of inflammatory factors through western blotting; (H) iCRT3 significantly reversed the influence of resveratrol on inflammatory factors expression. *P 2O2, + P

Figure 8. iCRT3 significantly reversed the influence of resveratrol on apoptosis in vitro. (A) Influence of iCRT3 on the Wnt signaling related proteins expression through western blotting; (B) CRT3 significantly inhibited the protein expression of Wnt signaling related proteins; (C) iCRT3 significantly inhibited the mRNA expression of Wnt signaling related proteins; (D) The influence of iCRT3 on the apoptosis was investigated; (E) iCRT3 significantly reversed the influence of resveratrol on apoptosis in vitro; (F) iCRT3 significantly reversed the influence of resveratrol on cell proliferation in vitro; (G) Influence of iCRT3 on the protein expression of inflammatory factors through western blotting; (H) iCRT3 significantly reversed the influence of resveratrol on inflammatory factors expression. *P <0.05 compared with group control, #P <0.05 compared with group H2O2, + P <0.05 compared with group SCI+resveratrol. The experiments were repeated at least 3 independent times.