Research Paper Volume 13, Issue 21 pp 24251—24270

A prognostic fibroblast-related risk signature in colorectal cancer

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Figure 9.

Correlations with immune cells and immune responses. (A) The B lineage cells, T cells, and NK cells were negatively correlated with the risk score, whereas endothelial cells and monocytic lineage content were positively correlated with the risk score. (B) The main immune cell lineages including B lineage, T cells and NK cells are higher in low-risk group (P < 0.05) while endothelial cells and monocytic lineage are higher in high-risk group. (C) The immune checkpoint genes (PDCD1, CTLA4, HAVCR2, GZMA) expression between high-risk group and low-risk group. (D) The inflammation cytokine genes (IL10, TGFβ1, IFNG, TNF) expression between high-risk group and low-risk group.