Research Paper Volume 13, Issue 21 pp 24402—24416

miR-6745-TIMP1 axis inhibits cell growth and metastasis in gastric cancer

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Figure 2b.

TIMP1 promotes GC proliferation, migration and invasion. SGC-7901 and MGC-803 cells were transduced with TIMP1 expression plasmid (pTIMP1) or pcDNA3.1 as indicated. (D, E) Cell metastasis was determined by Scratch wound assays (D) or Transwell migration and Matrigel invasion assays (E). (F) The expression levels of the cell proliferation marker Ki67 were detected by immunofluorescence. Data represent the means ± SEM. **P < 0.01.