Research Paper Volume 13, Issue 22 pp 24786—24794

Excluding embryos with two novel mutations in FREM2 gene by the next-generation sequencing-based single nucleotide polymorphism haplotyping


Figure 3. Conservation analysis of affected amino acids among six primate species. Evolutionary conservation of the mutations within FREM2 across species is analyzed. The positions of 2 mutations p.Gln897Term (A) and p.V2516GfsX10 (B) are indicated in red boxes.