Research Paper Volume 13, Issue 23 pp 25564—25577

CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammation

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Figure 1. CHIP levels were increased after MCAO. (A, B) Western blot and quantitative analysis of CHIP at different time points after reperfusion in the sham and MCAO surgery groups. (C) The mRNA expression of CHIP. (D, E) Immunostaining and quantitative analysis of CHIP at 24 h after reperfusion in the sham and MCAO surgery groups. Scale bar =100 μm. Data are presented as the mean ± SEM; n=6/group; ns, no significant difference vs. sham group; *P < 0.05 vs. sham group.