Research Paper Volume 13, Issue 23 pp 25564—25577

CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammation

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Figure 3. CHIP overexpression alleviated brain injury after MCAO. (A) TTC staining showed the cerebral infarct volume. (B) Quantitative analysis of the cerebral infarct volume. (C) HE and Nissl staining indicated the morphological characteristics. (D) Neurological scores. (E) Brain water content. Scale bar =50 μm. Data are presented as the mean ± SEM; n=6/each group and neurological scores n=10/each group; ns, no significant difference; *P < 0.05.