Research Paper Volume 13, Issue 23 pp 25564—25577

CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammation


Figure 4. CHIP overexpression reduced neuronal cell death after MCAO. (A) TUNEL+ cells in the cortex and hippocampus CA1 regions were detected by TUNEL/NeuN staining after sham or MCAO surgery. (B) Quantitative analysis of total TUNEL+ ratio. Scale bar =100 μm. Data are presented as the mean ± SEM; n=6/group; ns, no significant difference; *P < 0.05.