Research Paper Volume 13, Issue 23 pp 25564—25577
CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammation
Figure 6. CHIP overexpression alleviated the inflammatory response after MCAO. (A–D) Proinflammatory mediators (TNF-α, IL-1β, IL-6) and anti-inflammatory mediator (IL-10) levels in the serum after MCAO. (E–H) Pro-inflammatory mediators (TNF-α, IL-1β, IL-6) and anti-inflammatory mediator (IL-10) in peri-infarct tissues after MCAO. Data are presented as the mean ± SEM; n=6/group; ns, no significant difference; *P < 0.05.