NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway

Jinli Wang; Xueqin Song; Guojun Tan; Pengtao Sun; Li Guo; Ning Zhang; Jueqiong Wang; Bin Li

doi:doi:10.18632/aging.203781

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Research Paper Volume 13, Issue 24 pp 25931—25943

NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway

Figure 1. (A) GSE135511 differential gene volcano map. (B) GSE135511 heat map of differential gene cluster analysis. (C) GSE131279 differential gene volcano map. (D) GSE131279 heat map of differential gene cluster analysis. (E, F) GO enrichment analysis of the up-regulated pathway.