Research Paper Volume 14, Issue 10 pp 4305—4325
MRTF-A-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models
Figure 6. mTOR was the target of miR-1273g-3p. (A) A complementary pairing area or mutant area was shown between miR-1273g-3p and 3′-UTR mTOR with the wild type or mutant type, respectively. (B) The dual luciferase reporter assay. (C–E) The protein expression of mTOR and p-mTOR was detected by western blot. Data represent means ± SEM of 3 independent experiments. *P < 0.05, **P < 0.01 and ***P < 0.001 (one-way ANOVA, Tukey’s Multiple Comparison Test).