Research Paper Volume 14, Issue 4 pp 1822—1835

Downregulated exosome-associated gene FGF9 as a novel diagnostic and prognostic target for ovarian cancer and its underlying roles in immune regulation

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Figure 5. The relationship between the expression level of FGF9 and immune responses of OC patients. (A) The diagraph showing the relation between FGF9 expression and 24 types of immune cells. The size of the dots represented the values of Spearman r (p < 0.05). (B) The pictures downloaded from TISIDB database showing the relationship between FGF9 and immune infiltration cells, such as activated dendritic cells (aDC), Treg, Th17 cells, NK CD56dim cells (p < 0.05). (C) The Timer database showing the relationship between the expression level of FGF9 and immune infiltration cells. (D, E) The heatmap and scatterplot depicting FGF9 expression was negatively correlated to VSIR or CTLA4.