Research Paper Volume 14, Issue 6 pp 2507—2512
Evaluation of the effect of age of the younger mice on the rejuvenation of the older mice by heterochronic parabiosis
Figure 3. Immunofluorescence staining of the liver. Red signifies IL-6. IL-6 expression is observed along the wall of the interlobular vein. The 67-week-old mice joined with 4-week-old mice have decreased fluorescence compared to the 67-week-old mice joined with 8-week mice, suggesting that there is an effect of parabiosis on younger individuals. Abbreviations: CY: control young; CO: control old; O w/4: 67-week-old mice joined with 4-week-old mice; O w/8: 67-week-old mice joined with 8-week-old mice.