Research Paper Volume 14, Issue 7 pp 3216—3232

Trehalose inhibits ferroptosis via NRF2/HO-1 pathway and promotes functional recovery in mice with spinal cord injury

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Figure 2. Trehalose attenuates the damaged area and motor neuron loss of SCI in mice. (A) General picture of the spinal cord on day 28 after SCI; (B) HE staining of the spinal cord on day 28 after SCI; (C) Quantification of damage area; (D) NeuN staining around the spinal cord injury area on the 28th day after SCI; (E) Quantitative analysis of neuronal cells. *p < 0.05 compared with the Sham group, #p < 0.05 compared with the SCI group.