Research Paper Volume 14, Issue 7 pp 3293—3312

Abnormal phenotype of Nrf2 is associated with poor prognosis through hypoxic/VEGF-A-Rap1b/VEGFR2 pathway in gastric cancer

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Figure 3. Relative expression of mRNA. (A) Expression of Nrf2, HO-1 and HIF-1α in GC cells cultured under a hypoxic condition. (B) Expression of Nrf2 in GC cells after they were transfected with negative control siRNA or Nrf2 siRNAs (siNrf2-1498, siNrf2-2081 and siNrf2-2226). (C) Expression of Nrf2, HO-1 and HIF-1α in GC cells after they were transfected with siNrf2-1498 and cultured under a hypoxic condition. (*P<0.05, **P<0.001).