Research Paper Volume 14, Issue 7 pp 3313—3324

SNP rs322931 (C>T) in miR-181b and rs7158663 (G>A) in MEG3 aggravate the inflammatory response of anal abscess in patients with Crohn’s disease

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Figure 3. The expressions of CRP (A) and SSA (B) were both progressively elevated in the peripheral blood of Crohn’s disease patients carrying rs7158663 GG/rs322931 CC (N=76), rs7158663 AG+AA/rs322931 CC (N=62), rs7158663 GG/rs322931 CT+TT (N=36), and rs7158663 AG+AA/rs322931 CT+TT (N=32) genotypes (* P value < 0.05 vs. rs7158663 GG/rs322931 CC group; ** P value < 0.05 vs. rs7158663 AG+AA/rs322931 CC group; # P value < 0.05 vs. rs7158663 GG/rs322931 CT+TT group; 3 biological repeats).