Priority Research Paper Volume 14, Issue 10 pp 4195—4210

Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism

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Figure 5. Electron microscopy images of autophagosomes in mouse liver. Control animal (AD) vs. Chloroquine-treated animal (EH). Highlighted are glycogen granules (white arrow) in controls and autophagosomes (black arrow) in the liver of treated animals. Scale bar, 0,5 μm. N = 3 for each group.