Research Paper Volume 14, Issue 10 pp 4220—4246
Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence
Figure 6. t-SNE and UMAP profiles for single target morphological profiles. (A–D) t-SNE and UMAP plots for oncogene-induced senescence (OIS), paracrine senescence (Paracrine), HMF replicative senescence (HMF RS) and HDF replicative senescence (HDF RS) models. Proliferating conditions (Blue): vector induction (Vec_Ind), vector conditioned media (Vec_CM), HMF early proliferating (HMF_EP) and HDF early proliferating (HDF_EP). Senescence conditions (Orange): OIS induction (OIS_Ind), OIS conditioned media (OIS_CM), HMF deep senescence (HMF_DS), HDF deep senescence (HDF_DS).