Research Paper Volume 14, Issue 16 pp 6689—6715
Prognostic alternative splicing events related splicing factors define the tumor microenvironment and pharmacogenomic landscape in lung adenocarcinoma
Figure 5. SFs patterns and corresponding TME characteristics. (A) Consensus clustering matrix for k = 3. (B) Principal component analysis (PCA) was conducted in distinct SFs patterns. (C) Survival analyses for three distinct SFs patterns based on six GEO cohorts (GSE13213, GSE37745, GSE31210, GSE3141, GSE30219 and GSE50081). (D) Heatmap of 16 SFs expression in LUAD patients. (E) TME cell infiltrating abundances in three SFs clusters. (F) Difference of immune functions in three SFs clusters. (G) Difference of other tumor-related biological processes.